Learn More
Download Product Summary
Technical Information & Research
The Technical Information & Research section provides extensive materials on LabDiet® phytoestrogen research and diets, nutrient & contaminant levels in LabDiet® certified diets, specie intake and biological data, certified analysis technical data and bibliography search data around LabDiet products.
-
PHYTOESTROGRENS
THE FACTS ABOUT ISOFLAVONES: A LOOK AT THE BIG PICTURE
Isoflavones, the most common form of phytoestrogens, are detectable in most all diets fed to laboratory animals. Isoflavones are not bad for animals; however more and more researchers need to verify the levels contained in the diets for specific study area. Before making your decision about isoflavones, there is more that you should know.
FACTS ON ISOFLAVONES IN DIETS
Click the link below to find information to assist you in making the correct choice for your lab animals.
- Isoflavones (IF) are a common class of phytoestrogens. They are plant-derived compounds capable of estrogenic or antiestrogenic effects on the animals consuming them. Isoflavones are structural mimics of endogenous 17ß-estradiol (Seielstad, et al., 1995).
- IFs are nothing new. As early as the 1920s, IFs were found to affect body metabolism and in the 1940s, IFs found in red clover were found to affect sheep fertility.
- Since the early 1990s, with an increase in endocrine disruptor (ED) awareness, IFs have been identified as contributing factors that may affect the outcome of such studies.
- In the lab community, some advocate feeding low IF diets to all of their animals. However, others feel the low IF diets should only be used where appropriate.
-
NUTRIENT & CONTAMINENT LEVELS
Nutrient and Contamination Levels in LabDiet® Certified Laboratory Animal Feeds
Based on data compiled from 1993-2012 by Purina LabDiet® and in conjunction with an independent laboratory.
Animal diets used in laboratory studies must provide consistent and proper nutrition.1 To assist in experimental control, feed manufacturers must ensure that all batches of feed meet approved nutritional profiles.2 Certified diets for laboratory animals are commonly used in toxicological studies where control of contaminants, such as pesticides and heavy metals, is imperative. Certified LabDiet® products manufactured by PMI are analyzed prior to sale and guaranteed not to exceed established maximum concentrations of key contaminants. PMI controls variables that could adversely affect study animals and possibly lead to inaccurate conclusions. Certified LabDiet® products meet the recommendations of the FDA's Good Laboratory Practices Program.
This report is an update to our 2007 published bulletin "Nutrient and Contaminant Levels in LabDiet® Certified Laboratory Animal Feeds: 15-Year Technical Bulletin" which reports the results of our ongoing efforts to provide diets that are consistent from batch to batch as well as year to year. The data reported in this bulletin includes that from 1993 to 2007 and now 2008 to 2012.
20-YEAR TECHNICAL BULLETIN UPDATE
- INTAKE & BIOLOGICAL DATA
-
TECHNICAL UPDATES
The LabDiet® Technical Updates contains the following analysis:
- Microbiology Report
- Summary of Nutritional Analyses
- Contaminants Report
Related Documents- 2013 LabDiet Update
- 2012 LabDiet Update
- 2011 LabDiet Update
- 2010 LabDiet Update
- 2009 LabDiet Update
- 2008 LabDiet Update
- 2007 LabDiet Update
- 2006 LabDiet Update
- 2005 LabDiet Update
- 2004 LabDiet Update
- 2003 LabDiet Update
- 2002 LabDiet Update
- 2001 LabDiet Update
- 2000 LabDiet Update
- 1999 LabDiet Update
- 1998 LabDiet Update
- 1997 LabDiet Update
- 1996 LabDiet Update
-
BIBLIOGRAPHY
Research Articles relating to LabDiet products using Google Scholar.
Search terms: